I have been working with a client recently, helping with their sciatic pain. Luckily they have not had the pain for a long period, which can be helpful when treating. They were waking with shooting pains in the morning and having their sleep disturbed by the pain also.
Form the very first treatment they reacted well and there was an immediate reduction in the pain they were experiencing. This has continued with each subsequent treatment and they have now been pain free for three weeks.
I had previously worked with a few clients, many years ago, who were also experiencing sciatic pain and generally there has always been positive reactions.